For students

We offer the following topics:

Doctoral theses

 

Diploma theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Regulation of expression of genes involved in Corynebacterium glutamicum stress response induced by aromatic contaminants in environment
  • Purification of RNA polymerase from Corynebacterium glutamicum and its use in study of transcription
  • Functions of sigma factors of RNA polymerase in expresion of stress response genes in Rhodococcus strains degrading environmental contaminants
  • Chemostress response in bacterial degrader of phenol Rhodococcus erythropolis
  • Isolation and purification of nitrile metabolism enzymes and study of their catalytic properties

 

Supervisor: RNDr. Maria Brennerová, CSc.

  • Metagenomic analysis of microbial communities in groundwaters contaminated with chlorinated organic pollutants

 

Bachelor theses

 

 

Handling theses:

Doctoral theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Expression of genes encoding novel enzymes of microbial aldoxime and nitrile metabolism and characterization of enzyme activities (Robert Rädisch)
  • Function of SigB stress sigma factor of RNA polymerase in Corynebacterium glutamicum and Rhodococcus erythropolis (Andrej Rapoport)
  • Overlaps of stress regulons in corynebacteria and rhodococci (Jan Blumenstein)
  • Stress responses in bacterial degrader of aromatic contaminants of environment Rhodococcus erythropolis (Lukáš Plašil)

 

Supervisor: RNDr. Maria Brennerová, CSc.

  • New genes with functional priority for degradation of aromatic hydrocarbons in highly contaminated environment

 

Diploma theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Analysis of regulatory networks controlled by sigma factors in bacteria of Mycolata group using Corynebacterium glutamicum model (Tomáš Kučera)

 

Bachelor theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Overlaps of sigma factor regulons in Corynebacterium glutamicum

 

Supervisor: RNDr. Václav Štěpánek, CSc.

  • Function of sigma factors in strains of genus Rhodococcus
  • Responses of Rhodococcus strains to heavy metal stress

 

 

 

Defended theses:

Doctoral theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Function of stress sigma factors of RNA polymerase SigD, SigE, SigH and SigM in transcription regulation network of Corynebacterium glutamicum (Hana Dostálová)
  • Analysis of genes coding for enzymes involved in degradation of aromatic pollutants in Rhodococcus erythropolis (Juraj Szököl)
  • Regulation of the gene expression in the strain Rhodococcus erythropolis degrading xenobiotics (Monika Knoppová)
  • Study of regulation of branched-chain amino acid biosynthesis in C. glutamicum and construction of valine producing strain (Jiří Holátko)
  • Development and use of gene manipulations in phenol-degrading Rhodococcus erythropolis (Martin Veselý)

 

Supervisor: RNDr. Jan Nešvera, CSc.

  • The role of alternative sigma factors of RNA polymerase in regulation of gene expression in Corynebacterium glutamicum (Radoslav Šilar)
  • Characterization of Corynebacterium glutamicum promoters responding to increase of temperature (Martina Zemanová)

 

Supervisor: RNDr. Maria Brennerová, CSc.

  • Divergent organohalide-respiring consortia in PCB-contaminated sediments (Martina Mikešová)

 

Diploma theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Expression of genes for the conversion of nitriles and amides in Rhodococcus erythropolis (Martin Kracík)
  • Characteristics of expression vectors for Corynebacterium glutamicum and their use for studies of sigma factors of RNA polymerase (Pavla Dvořáková)

 

Supervisor: RNDr. Jan Nešvera, CSc.

  • Function of alternative sigma factors of RNA polymerase in stress response of Corynebacterium glutamicum (Hana Dostálová)
  • Promoters of Corynebacterium glutamicum controlled by alternative sigma factors of RNA polymerase

 

Supervisor: RNDr. Maria Brennerová, CSc.

  • Studies on xenobiotic degradation potential of soil and rhizosphere microbial communities from heavily polluted aquifers in Czech Republic

 

Supervisor: RNDr. Václav Štěpánek, CSc.

  • Hybrid sigma factors of RNA polymerase in Corynebacterium glutamicum (Jan Blumenstein)

 

Bachelor theses

Supervisor: Ing. Miroslav Pátek, CSc.

  • Stress responses in Rhodococcus strains
  • Functions of sigma factors of RNA polymerase in Corynebacterium glutamicum (Pavla Dvořáková)
  • Regulatory network controlled by sigma factors of RNA polymerase in Corynebacterium glutamicum (Tomáš Kučera)